{"id":197096,"date":"2024-01-08T14:43:23","date_gmt":"2024-01-08T13:43:23","guid":{"rendered":"https:\/\/naturdao.com\/food-intolerance-the-role-of-histamine\/"},"modified":"2024-03-04T14:14:34","modified_gmt":"2024-03-04T13:14:34","slug":"food-intolerance-the-role-of-histamine","status":"publish","type":"post","link":"https:\/\/naturdao.com\/en\/food-intolerance-the-role-of-histamine\/","title":{"rendered":"Food Intolerance: The Role of Histamine"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"197096\" class=\"elementor elementor-197096 elementor-196077\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4106671 e-flex e-con-boxed e-con e-parent\" data-id=\"4106671\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-f687bb7 e-flex e-con-boxed e-con e-child\" data-id=\"f687bb7\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-808b577 e-con-full e-flex e-con e-child\" data-id=\"808b577\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c8cd2e6 elementor-widget elementor-widget-image\" data-id=\"c8cd2e6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"575\" height=\"818\" src=\"https:\/\/naturdao.com\/wp-content\/uploads\/2024\/01\/the-role-of-.jpg\" class=\"attachment-large size-large wp-image-196128\" alt=\"\" srcset=\"https:\/\/naturdao.com\/wp-content\/uploads\/2024\/01\/the-role-of-.jpg 575w, https:\/\/naturdao.com\/wp-content\/uploads\/2024\/01\/the-role-of--211x300.jpg 211w\" sizes=\"(max-width: 575px) 100vw, 575px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-fc68a31 e-con-full e-flex e-con e-child\" data-id=\"fc68a31\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-84d429b elementor-widget elementor-widget-theme-post-title elementor-page-title elementor-widget-heading\" data-id=\"84d429b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"theme-post-title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Food Intolerance: The Role of Histamine<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-140c460 elementor-align-start elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"140c460\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-user\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Yulia O. Shulpekova, Vladimir M. Nechaev, Irina R. Popova, Tatiana A. Deeva, Arthur T. Kopylov, Kristina A. Malsagova, Anna L. Kaysheva, Vladimir T. Ivashkin<br><\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-newspaper\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Nutrients 2021, 13, 3207<br><\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/doi.org\/10.3390\/nu13093207\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-archive\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">https:\/\/doi.org\/10.3390\/nu13093207 <br><\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"far fa-comment\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">ENGLISH<br><\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-cd5f085 e-flex e-con-boxed e-con e-parent\" data-id=\"cd5f085\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-34379fd elementor-widget elementor-widget-text-editor\" data-id=\"34379fd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"text-decoration: underline;\"><strong>ABSTRACT<\/strong><\/span><\/p>\n<p>Histamine is a natural amine derived from L-histidine. Although it seems that our knowledge about this molecule is wide and diverse, the importance of histamine in many regulatory processes is still enigmatic.<\/p>\n<p>The interplay between different types of histamine receptors and the compound may cause ample effects, including histamine intoxication and so-called histamine intolerance or non-allergic food intolerance, leading to disturbances in immune regulation, manifestation of gastroenterological symptoms, and neurological diseases.<\/p>\n<p>Most cases of clinical manifestations of histamine intolerance are non-specific due to tissue-specific distribution of different histamine receptors and the lack of reproducible and reliable diagnostic markers.<\/p>\n<p>The diagnosis of histamine intolerance is fraught with difficulties, in addition to challenges related to the selection of a proper treatment strategy, the regular course of recovery, and reduced amelioration of chronic symptoms due to inappropriate treatment prescription.<\/p>\n<p>Here, we reviewed a history of histamine uptake starting from the current knowledge about its degradation and the prevalence of histamine precursors in daily food, and continuing with the receptor interactions after entering and the impacts on the immune, central nervous, and gastrointestinal systems.<\/p>\n<p>The purpose of this review is to build an extraordinarily specific method of histamine cycle assessment in regard to non-allergic intolerance and its possible dire consequences that can be suffered.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6ea320f e-flex e-con-boxed e-con e-parent\" data-id=\"6ea320f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f4bb81e elementor-align-center elementor-widget elementor-widget-button\" data-id=\"f4bb81e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-xl\" href=\"https:\/\/www.mdpi.com\/2072-6643\/13\/9\/3207\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-file-pdf\"><\/i>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Read full article <\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Yulia O. Shulpekova, Vladimir M. Nechaev, Irina R. Popova, Tatiana A. Deeva, Arthur T. Kopylov, Kristina A. Malsagova, Anna L. Kaysheva, Vladimir T. Ivashkin Nutrients 2021, 13, 3207 https:\/\/doi.org\/10.3390\/nu13093207 ENGLISH ABSTRACT Histamine is a natural amine derived from L-histidine. Although it seems that our knowledge about this molecule is wide and diverse, the importance of [&hellip;]<\/p>\n","protected":false},"author":1097,"featured_media":196449,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[169],"tags":[],"class_list":["post-197096","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-studies"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.0.1 - aioseo.com -->\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"yasmina\"\/>\n\t<meta name=\"google-site-verification\" content=\"googlec0b8607c1a0a6fdc.html\" \/>\n\t<link rel=\"canonical\" href=\"https:\/\/naturdao.com\/en\/food-intolerance-the-role-of-histamine\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO (AIOSEO) 5.0.0.1\" \/>\n\t\t<script type=\"application\/ld+json\" class=\"aioseo-schema\">\n\t\t\t{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/food-intolerance-the-role-of-histamine\\\/#article\",\"name\":\"Food Intolerance: The Role of Histamine | NATURDAO\",\"headline\":\"Food Intolerance: The Role of Histamine\",\"author\":{\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/author\\\/yasmina\\\/#author\"},\"publisher\":{\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/#organization\"},\"image\":{\"@type\":\"ImageObject\",\"url\":\"https:\\\/\\\/naturdao.com\\\/wp-content\\\/uploads\\\/2024\\\/01\\\/Intolerancias-Alimentarias-El-rol-de-la-histamina-scaled.jpg\",\"width\":2560,\"height\":512},\"datePublished\":\"2024-01-08T14:43:23+01:00\",\"dateModified\":\"2024-03-04T14:14:34+01:00\",\"inLanguage\":\"en-US\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/food-intolerance-the-role-of-histamine\\\/#webpage\"},\"isPartOf\":{\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/food-intolerance-the-role-of-histamine\\\/#webpage\"},\"articleSection\":\"Studies, Optional\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/food-intolerance-the-role-of-histamine\\\/#breadcrumblist\",\"itemListElement\":[{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/#listItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/naturdao.com\\\/en\\\/\",\"nextItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/category\\\/studies\\\/#listItem\",\"name\":\"Studies\"}},{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/category\\\/studies\\\/#listItem\",\"position\":2,\"name\":\"Studies\",\"item\":\"https:\\\/\\\/naturdao.com\\\/en\\\/category\\\/studies\\\/\",\"nextItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/food-intolerance-the-role-of-histamine\\\/#listItem\",\"name\":\"Food Intolerance: The Role of Histamine\"},\"previousItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/#listItem\",\"name\":\"Home\"}},{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/food-intolerance-the-role-of-histamine\\\/#listItem\",\"position\":3,\"name\":\"Food Intolerance: The Role of Histamine\",\"previousItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/category\\\/studies\\\/#listItem\",\"name\":\"Studies\"}}]},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/#organization\",\"name\":\"GLOBAL MOPI SL\",\"description\":\"Complemento alimenticio de Diamino Oxidasa - 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