{"id":197154,"date":"2024-01-17T12:41:15","date_gmt":"2024-01-17T11:41:15","guid":{"rendered":"https:\/\/naturdao.com\/lyophilised-legume-sprouts-as-a-functional-ingredient-for-diamine-oxidase-enzyme-2-supplementation-in-histamine-intolerance\/"},"modified":"2024-03-04T14:03:59","modified_gmt":"2024-03-04T13:03:59","slug":"lyophilised-legume-sprouts-as-a-functional-ingredient-for-diamine-oxidase-enzyme-2-supplementation-in-histamine-intolerance","status":"publish","type":"post","link":"https:\/\/naturdao.com\/en\/lyophilised-legume-sprouts-as-a-functional-ingredient-for-diamine-oxidase-enzyme-2-supplementation-in-histamine-intolerance\/","title":{"rendered":"Lyophilised legume sprouts as a functional ingredient for diamine oxidase enzyme 2 supplementation in histamine intolerance"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"197154\" class=\"elementor elementor-197154 elementor-196586\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4106671 e-flex e-con-boxed e-con e-parent\" data-id=\"4106671\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-f687bb7 e-flex e-con-boxed e-con e-child\" data-id=\"f687bb7\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-808b577 e-con-full e-flex e-con e-child\" data-id=\"808b577\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c8cd2e6 elementor-widget elementor-widget-image\" data-id=\"c8cd2e6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"576\" height=\"768\" src=\"https:\/\/naturdao.com\/wp-content\/uploads\/2024\/01\/Legumes_Dao.jpg\" class=\"attachment-large size-large wp-image-196601\" alt=\"\" srcset=\"https:\/\/naturdao.com\/wp-content\/uploads\/2024\/01\/Legumes_Dao.jpg 576w, https:\/\/naturdao.com\/wp-content\/uploads\/2024\/01\/Legumes_Dao-225x300.jpg 225w\" sizes=\"(max-width: 576px) 100vw, 576px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-fc68a31 e-con-full e-flex e-con e-child\" data-id=\"fc68a31\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-84d429b elementor-widget elementor-widget-theme-post-title elementor-page-title elementor-widget-heading\" data-id=\"84d429b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"theme-post-title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Lyophilised legume sprouts as a functional ingredient for diamine oxidase enzyme 2 supplementation in histamine intolerance<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-140c460 elementor-align-start elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"140c460\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-user\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Comas Bast\u00e9, Oriol Latorre Moratalla, Mariluz Rabell-Gonz\u00e1lez, Judit Veciana Nogu\u00e9s, Mar\u00eda Teresa Vidal Carou, Ma. Carmen<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-newspaper\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">LWT - Food Science and Technology, Volume 125, May 2020, 109201<br><\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/doi.org\/10.1016\/j.lwt.2020.109201\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-archive\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">https:\/\/doi.org\/10.3390\/nu13093207 <br><\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"far fa-comment\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">ENGLISH<br><\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-cd5f085 e-flex e-con-boxed e-con e-parent\" data-id=\"cd5f085\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-34379fd elementor-widget elementor-widget-text-editor\" data-id=\"34379fd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"text-decoration: underline;\"><strong>ABSTRACT<\/strong><\/span><\/p>\n<p>Diamine oxidase (DAO) is one of the key enzymes involved in the degradation of dietary histamine. An imbalance of histamine scavenging systems leads to histamine intolerance, a diet-related disorder that may be tackled by following a low-histamine diet.<\/p>\n<p>Recently, the supplementation with exogenous DAO enzyme of animal origin has received the green light as a novel food to enhance intestinal degradation of histamine.<\/p>\n<p>This work performed a screening for histamine-degrading capacity of Leguminosae species in order to explore its potential suitability as a plant-derived active ingredient of enzymatic supplements. In vitro DAO activity was determined both in raw pulses and lyophilized sprouts by an enzymatic assay coupled to UHPLC-FLD, and several germination and storage conditions were assessed.<\/p>\n<p>The sprouts of edible legumes showed an in vitro histamine-degrading capacity ranging from 36.0 to 408.3 mU g^(-1), much higher than that found for the non-germinated seeds (0.14 &#8211; 1.95 mU g^(-1)). The germination of legume seeds for 6 days in darkness provided the maximum DAO activity. Only the freezing storage of the lyophilized sprouts kept the enzymatic activity intact for at least 12 months.<\/p>\n<p>These results demonstrate that certain edible legumes could be suitable for the formulation of DAO supplements for the treatment of histamine intolerance.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6ea320f e-flex e-con-boxed e-con e-parent\" data-id=\"6ea320f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f4bb81e elementor-align-center elementor-widget elementor-widget-button\" data-id=\"f4bb81e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-xl\" href=\"https:\/\/diposit.ub.edu\/dspace\/bitstream\/2445\/163063\/1\/699701.pdf\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-file-pdf\"><\/i>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Read full article <\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Comas Bast\u00e9, Oriol Latorre Moratalla, Mariluz Rabell-Gonz\u00e1lez, Judit Veciana Nogu\u00e9s, Mar\u00eda Teresa Vidal Carou, Ma. Carmen LWT &#8211; Food Science and Technology, Volume 125, May 2020, 109201 https:\/\/doi.org\/10.3390\/nu13093207 ENGLISH ABSTRACT Diamine oxidase (DAO) is one of the key enzymes involved in the degradation of dietary histamine. An imbalance of histamine scavenging systems leads to histamine [&hellip;]<\/p>\n","protected":false},"author":1097,"featured_media":196590,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[169],"tags":[],"class_list":["post-197154","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-studies"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.0.1 - aioseo.com -->\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"yasmina\"\/>\n\t<meta name=\"google-site-verification\" content=\"googlec0b8607c1a0a6fdc.html\" \/>\n\t<link rel=\"canonical\" href=\"https:\/\/naturdao.com\/en\/lyophilised-legume-sprouts-as-a-functional-ingredient-for-diamine-oxidase-enzyme-2-supplementation-in-histamine-intolerance\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO (AIOSEO) 5.0.0.1\" \/>\n\t\t<script type=\"application\/ld+json\" class=\"aioseo-schema\">\n\t\t\t{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/lyophilised-legume-sprouts-as-a-functional-ingredient-for-diamine-oxidase-enzyme-2-supplementation-in-histamine-intolerance\\\/#article\",\"name\":\"Lyophilised legume sprouts as a functional ingredient for diamine oxidase enzyme 2 supplementation in histamine intolerance | NATURDAO\",\"headline\":\"Lyophilised legume sprouts as a functional ingredient for diamine oxidase enzyme 2 supplementation in histamine intolerance\",\"author\":{\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/author\\\/yasmina\\\/#author\"},\"publisher\":{\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/#organization\"},\"image\":{\"@type\":\"ImageObject\",\"url\":\"https:\\\/\\\/naturdao.com\\\/wp-content\\\/uploads\\\/2024\\\/01\\\/estudis-scaled.jpg\",\"width\":2560,\"height\":555},\"datePublished\":\"2024-01-17T12:41:15+01:00\",\"dateModified\":\"2024-03-04T14:03:59+01:00\",\"inLanguage\":\"en-US\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/lyophilised-legume-sprouts-as-a-functional-ingredient-for-diamine-oxidase-enzyme-2-supplementation-in-histamine-intolerance\\\/#webpage\"},\"isPartOf\":{\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/lyophilised-legume-sprouts-as-a-functional-ingredient-for-diamine-oxidase-enzyme-2-supplementation-in-histamine-intolerance\\\/#webpage\"},\"articleSection\":\"Studies, Optional\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/lyophilised-legume-sprouts-as-a-functional-ingredient-for-diamine-oxidase-enzyme-2-supplementation-in-histamine-intolerance\\\/#breadcrumblist\",\"itemListElement\":[{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/#listItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/naturdao.com\\\/en\\\/\",\"nextItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/category\\\/studies\\\/#listItem\",\"name\":\"Studies\"}},{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/category\\\/studies\\\/#listItem\",\"position\":2,\"name\":\"Studies\",\"item\":\"https:\\\/\\\/naturdao.com\\\/en\\\/category\\\/studies\\\/\",\"nextItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/lyophilised-legume-sprouts-as-a-functional-ingredient-for-diamine-oxidase-enzyme-2-supplementation-in-histamine-intolerance\\\/#listItem\",\"name\":\"Lyophilised legume sprouts as a functional ingredient for diamine oxidase enzyme 2 supplementation in histamine intolerance\"},\"previousItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/#listItem\",\"name\":\"Home\"}},{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/lyophilised-legume-sprouts-as-a-functional-ingredient-for-diamine-oxidase-enzyme-2-supplementation-in-histamine-intolerance\\\/#listItem\",\"position\":3,\"name\":\"Lyophilised legume sprouts as a functional ingredient for diamine oxidase enzyme 2 supplementation in histamine intolerance\",\"previousItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/category\\\/studies\\\/#listItem\",\"name\":\"Studies\"}}]},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/#organization\",\"name\":\"GLOBAL MOPI SL\",\"description\":\"Complemento alimenticio de Diamino Oxidasa - 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