{"id":199012,"date":"2024-04-10T10:35:27","date_gmt":"2024-04-10T08:35:27","guid":{"rendered":"https:\/\/naturdao.com\/measurement-of-diamine-oxidase-dao-during-low-histamine-or-ordinary-diet-in-patients-with-histamine-intolerance\/"},"modified":"2024-07-19T14:38:06","modified_gmt":"2024-07-19T12:38:06","slug":"measurement-of-diamine-oxidase-dao-during-low-histamine-or-ordinary-diet-in-patients-with-histamine-intolerance","status":"publish","type":"post","link":"https:\/\/naturdao.com\/en\/measurement-of-diamine-oxidase-dao-during-low-histamine-or-ordinary-diet-in-patients-with-histamine-intolerance\/","title":{"rendered":"Measurement of diamine oxidase (DAO) during low-histamine or ordinary diet in patients with histamine intolerance"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"199012\" class=\"elementor elementor-199012 elementor-198804\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4106671 e-flex e-con-boxed e-con e-parent\" data-id=\"4106671\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-f687bb7 e-flex e-con-boxed e-con e-child\" data-id=\"f687bb7\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-808b577 e-con-full e-flex e-con e-child\" data-id=\"808b577\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c8cd2e6 elementor-widget elementor-widget-image\" data-id=\"c8cd2e6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"589\" height=\"735\" src=\"https:\/\/naturdao.com\/wp-content\/uploads\/2024\/07\/Measurement_of_diamine_oxidase_DAO_during_low-histamine_diet-.png\" class=\"attachment-large size-large wp-image-198809\" alt=\"\" srcset=\"https:\/\/naturdao.com\/wp-content\/uploads\/2024\/07\/Measurement_of_diamine_oxidase_DAO_during_low-histamine_diet-.png 589w, https:\/\/naturdao.com\/wp-content\/uploads\/2024\/07\/Measurement_of_diamine_oxidase_DAO_during_low-histamine_diet--240x300.png 240w\" sizes=\"(max-width: 589px) 100vw, 589px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-fc68a31 e-con-full e-flex e-con e-child\" data-id=\"fc68a31\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-84d429b elementor-widget elementor-widget-theme-post-title elementor-page-title elementor-widget-heading\" data-id=\"84d429b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"theme-post-title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Measurement of diamine oxidase (DAO) during low-histamine or ordinary diet in patients with histamine intolerance<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-140c460 elementor-align-start elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"140c460\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-user\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Georgios Rentzos, Adina Weisheit, Linda Ekerljung &amp; Jenny van Odijk <\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-newspaper\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">European Journal of Clinical Nutrition (2024) <br><\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-archive\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">https:\/\/doi.org\/10.1038\/s41430-024-01448-2 <br><\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"far fa-comment\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">ENGLISH<br><\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-cd5f085 e-flex e-con-boxed e-con e-parent\" data-id=\"cd5f085\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-34379fd elementor-widget elementor-widget-text-editor\" data-id=\"34379fd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"text-decoration: underline;\"><strong>ABSTRACTO<\/strong><\/span><\/p>\n<div class=\"flex-shrink-0 flex flex-col relative items-end\">\n<div class=\"pt-0.5 juice:pt-0\">\n<div class=\"gizmo-bot-avatar flex h-6 w-6 items-center justify-center overflow-hidden rounded-full juice:h-8 juice:w-8\">\n<div class=\"relative p-1 rounded-sm flex items-center justify-center bg-token-main-surface-primary text-token-text-primary h-8 w-8\">\n<p><strong>Background\/Objectives<\/strong><br \/>\nQuantification of diamine oxidase (DAO) concentrations in serum has been proposed as an adjunctive diagnostic modality for the evaluation of histamine intolerance (HIT). Limited empirical data exist concerning the influence of dietary patterns on DAO levels.<\/p>\n<p><strong>Subjects\/Methods<\/strong><br \/>\nIn the context of a prospective study employing a crossover design, 18 individuals diagnosed with HIT were randomized to initiate either a low histamine diet (LHD) or a conventional mixed diet (MXD). Serum DAO concentrations were measured at the commencement of the study and following each dietary phase. A control group underwent analogous DAO assessments without imposition of dietary constraints.<\/p>\n<p><strong>Results<\/strong><br \/>\nDuring the time when a diet restricted in histamine was implemented, noticeable differences in changes in DAO levels did not become apparent when compared to the changes observed during the mixed (MXD) phase. Specifically, among the group, 10 of the 18 patients exhibited elevated DAO values subsequent to the LHD regimen, while the remaining eight displayed either reduced or unchanging DAO levels. The prevalence of elevated DAO levels in the LHD group did not differ significantly from that observed in the control group during the MXD phase. Additionally, during the LHD phase, patients reported a significant reduction in gastrointestinal and cutaneous symptoms.<\/p>\n<p><strong>Conclusions<\/strong><br \/>\nThis prospective investigation underscores the enduring utility of a histamine-restricted diet, coupled with structured dietary reintroduction, as an efficacious diagnostic approach for individuals presenting with suspected food-related histamine hypersensitivity. Notably, the measurement of DAO levels appears to furnish only a limited capacity to discern dietary-induced fluctuations. Notwithstanding, the dynamics of DAO alteration do not appear to exhibit a discernible association with specific dietary patterns, a finding consistent across both patient and control groups.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6ea320f e-flex e-con-boxed e-con e-parent\" data-id=\"6ea320f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f4bb81e elementor-align-center elementor-widget elementor-widget-button\" data-id=\"f4bb81e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-xl\" href=\"https:\/\/www.nature.com\/articles\/s41430-024-01448-2\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-file-pdf\"><\/i>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Read full article <\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Georgios Rentzos, Adina Weisheit, Linda Ekerljung &#038; Jenny van Odijk European Journal of Clinical Nutrition (2024) https:\/\/doi.org\/10.1038\/s41430-024-01448-2 ENGLISH ABSTRACTO Background\/Objectives Quantification of diamine oxidase (DAO) concentrations in serum has been proposed as an adjunctive diagnostic modality for the evaluation of histamine intolerance (HIT). Limited empirical data exist concerning the influence of dietary patterns on DAO [&hellip;]<\/p>\n","protected":false},"author":1097,"featured_media":198900,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[169],"tags":[],"class_list":["post-199012","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-studies"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.0.1 - aioseo.com -->\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"yasmina\"\/>\n\t<meta name=\"google-site-verification\" content=\"googlec0b8607c1a0a6fdc.html\" \/>\n\t<link rel=\"canonical\" href=\"https:\/\/naturdao.com\/en\/measurement-of-diamine-oxidase-dao-during-low-histamine-or-ordinary-diet-in-patients-with-histamine-intolerance\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO (AIOSEO) 5.0.0.1\" \/>\n\t\t<script type=\"application\/ld+json\" class=\"aioseo-schema\">\n\t\t\t{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/measurement-of-diamine-oxidase-dao-during-low-histamine-or-ordinary-diet-in-patients-with-histamine-intolerance\\\/#article\",\"name\":\"Measurement of diamine oxidase (DAO) during low-histamine or ordinary diet in patients with histamine intolerance | NATURDAO\",\"headline\":\"Measurement of diamine oxidase (DAO) during low-histamine or ordinary diet in patients with histamine intolerance\",\"author\":{\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/author\\\/yasmina\\\/#author\"},\"publisher\":{\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/#organization\"},\"image\":{\"@type\":\"ImageObject\",\"url\":\"https:\\\/\\\/naturdao.com\\\/wp-content\\\/uploads\\\/2024\\\/04\\\/3.png\",\"width\":800,\"height\":173},\"datePublished\":\"2024-04-10T10:35:27+02:00\",\"dateModified\":\"2024-07-19T14:38:06+02:00\",\"inLanguage\":\"en-US\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/measurement-of-diamine-oxidase-dao-during-low-histamine-or-ordinary-diet-in-patients-with-histamine-intolerance\\\/#webpage\"},\"isPartOf\":{\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/measurement-of-diamine-oxidase-dao-during-low-histamine-or-ordinary-diet-in-patients-with-histamine-intolerance\\\/#webpage\"},\"articleSection\":\"Studies, Optional\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/measurement-of-diamine-oxidase-dao-during-low-histamine-or-ordinary-diet-in-patients-with-histamine-intolerance\\\/#breadcrumblist\",\"itemListElement\":[{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/#listItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/naturdao.com\\\/en\\\/\",\"nextItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/category\\\/studies\\\/#listItem\",\"name\":\"Studies\"}},{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/category\\\/studies\\\/#listItem\",\"position\":2,\"name\":\"Studies\",\"item\":\"https:\\\/\\\/naturdao.com\\\/en\\\/category\\\/studies\\\/\",\"nextItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/measurement-of-diamine-oxidase-dao-during-low-histamine-or-ordinary-diet-in-patients-with-histamine-intolerance\\\/#listItem\",\"name\":\"Measurement of diamine oxidase (DAO) during low-histamine or ordinary diet in patients with histamine intolerance\"},\"previousItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/#listItem\",\"name\":\"Home\"}},{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/measurement-of-diamine-oxidase-dao-during-low-histamine-or-ordinary-diet-in-patients-with-histamine-intolerance\\\/#listItem\",\"position\":3,\"name\":\"Measurement of diamine oxidase (DAO) during low-histamine or ordinary diet in patients with histamine intolerance\",\"previousItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/category\\\/studies\\\/#listItem\",\"name\":\"Studies\"}}]},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/en\\\/#organization\",\"name\":\"GLOBAL MOPI SL\",\"description\":\"Complemento alimenticio de Diamino Oxidasa - 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