{"id":197118,"date":"2024-01-15T12:05:59","date_gmt":"2024-01-15T11:05:59","guid":{"rendered":"https:\/\/naturdao.com\/histamine-en-histamine-intolerantie\/"},"modified":"2024-03-04T14:07:27","modified_gmt":"2024-03-04T13:07:27","slug":"histamine-en-histamine-intolerantie","status":"publish","type":"post","link":"https:\/\/naturdao.com\/nl\/histamine-en-histamine-intolerantie\/","title":{"rendered":"Histamine en histamine-intolerantie"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"197118\" class=\"elementor elementor-197118 elementor-196411\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6fe7a379 e-flex e-con-boxed e-con e-parent\" data-id=\"6fe7a379\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-507b2fe8 e-flex e-con-boxed e-con e-child\" data-id=\"507b2fe8\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-776e6bdd e-con-full e-flex e-con e-child\" data-id=\"776e6bdd\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-64ede394 elementor-widget elementor-widget-image\" data-id=\"64ede394\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"622\" height=\"834\" src=\"https:\/\/naturdao.com\/wp-content\/uploads\/2024\/01\/histamine_and_histamine_intolerance.jpg\" class=\"attachment-large size-large wp-image-196421\" alt=\"\" srcset=\"https:\/\/naturdao.com\/wp-content\/uploads\/2024\/01\/histamine_and_histamine_intolerance.jpg 622w, https:\/\/naturdao.com\/wp-content\/uploads\/2024\/01\/histamine_and_histamine_intolerance-224x300.jpg 224w\" sizes=\"(max-width: 622px) 100vw, 622px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-54a06a6e e-con-full e-flex e-con e-child\" data-id=\"54a06a6e\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-563feb70 elementor-widget elementor-widget-theme-post-title elementor-page-title elementor-widget-heading\" data-id=\"563feb70\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"theme-post-title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Histamine en histamine-intolerantie<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1de6cbe6 elementor-align-start elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"1de6cbe6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-user\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Laura Maintz, Natalija Novak<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-newspaper\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">The American Journal of Clinical Nutrition Volume 85, Issue 5, May 2007, Pages 1185-1196<br><\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/doi.org\/10.1093\/ajcn\/85.5.1185\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-archive\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">https:\/\/doi.org\/10.1093\/ajcn\/85.5.1185 <br><\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"far fa-comment\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">ENGELS<br><\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-36446861 e-flex e-con-boxed e-con e-parent\" data-id=\"36446861\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2d5e9f70 elementor-widget elementor-widget-text-editor\" data-id=\"2d5e9f70\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"text-decoration: underline;\"><strong>SAMENVATTING<\/strong><\/span><\/p>\n<p>Histamine-intolerantie ontstaat door een onevenwicht tussen opgehoopte histamine en het vermogen om histamine af te breken.<\/p>\n<p>Histamine is een biogene amine die in verschillende mate voorkomt in veel voedingsmiddelen. Bij gezonde personen kan voedingshistamine snel worden ontgift door amine-oxidases, terwijl personen met een lage activiteit van amine-oxidases risico lopen op histaminetoxiciteit.<\/p>\n<p>Diamine oxidase (DAO) is het belangrijkste enzym voor het metabolisme van ingenomen histamine. Er is voorgesteld dat DAO, wanneer het fungeert als een secretoire prote\u00efne, verantwoordelijk kan zijn voor het verwijderen van extracellulaire histamine na de afgifte van mediatoren.<\/p>\n<p>Omgekeerd is histamine <em>N<\/em>-methyltransferase, het andere belangrijke enzym dat histamine inactief maakt, een cytosolisch eiwit dat histamine alleen kan omzetten in de intracellulaire ruimte van cellen.<\/p>\n<p>Een verminderde histamine-afbraak op basis van verminderde DAO-activiteit en het resulterende histamine-overschot kan talrijke symptomen veroorzaken die een allergische reactie nabootsen.<\/p>\n<p>De inname van histaminerijke voeding of van alcohol of medicijnen die histamine vrijgeven of DAO blokkeren, kan diarree, hoofdpijn, rhinoconjunctivale symptomen, astma, hypotensie, hartritmestoornissen, urticaria, jeuk, blozen en andere aandoeningen veroorzaken bij pati\u00ebnten met histamine-intolerantie.<\/p>\n<p>Symptomen kunnen worden verminderd door een histaminevrij dieet of worden ge\u00eblimineerd door antihistaminica. Vanwege de veelzijdige aard van de symptomen is het bestaan van histamine-intolerantie echter onderschat, en verder onderzoek op basis van dubbelblinde, placebo-gecontroleerde provocaties is nodig.<\/p>\n<p>Bij pati\u00ebnten bij wie de hierboven genoemde symptomen worden veroorzaakt door de overeenkomstige stoffen en die een negatieve diagnose hebben van allergie of interne aandoeningen, moet histamine-intolerantie worden overwogen als een onderliggend pathomechanisme.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-72010ac3 e-flex e-con-boxed e-con e-parent\" data-id=\"72010ac3\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-60047df9 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"60047df9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-xl\" href=\"https:\/\/ajcn.nutrition.org\/article\/S0002-9165(23)28053-3\/fulltext#%20\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-file-pdf\"><\/i>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Lees de volledige tekst<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Laura Maintz, Natalija Novak The American Journal of Clinical Nutrition Volume 85, Issue 5, May 2007, Pages 1185-1196 https:\/\/doi.org\/10.1093\/ajcn\/85.5.1185 ENGELS SAMENVATTING Histamine-intolerantie ontstaat door een onevenwicht tussen opgehoopte histamine en het vermogen om histamine af te breken. Histamine is een biogene amine die in verschillende mate voorkomt in veel voedingsmiddelen. Bij gezonde personen kan voedingshistamine [&hellip;]<\/p>\n","protected":false},"author":1097,"featured_media":196551,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[168],"tags":[],"class_list":["post-197118","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-studies-nl"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.0.1 - aioseo.com -->\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"yasmina\"\/>\n\t<meta name=\"google-site-verification\" content=\"googlec0b8607c1a0a6fdc.html\" \/>\n\t<link rel=\"canonical\" href=\"https:\/\/naturdao.com\/nl\/histamine-en-histamine-intolerantie\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO (AIOSEO) 5.0.0.1\" \/>\n\t\t<script type=\"application\/ld+json\" class=\"aioseo-schema\">\n\t\t\t{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/nl\\\/histamine-en-histamine-intolerantie\\\/#article\",\"name\":\"Histamine en histamine-intolerantie | NATURDAO\",\"headline\":\"Histamine en histamine-intolerantie\",\"author\":{\"@id\":\"https:\\\/\\\/naturdao.com\\\/nl\\\/author\\\/yasmina\\\/#author\"},\"publisher\":{\"@id\":\"https:\\\/\\\/naturdao.com\\\/nl\\\/#organization\"},\"image\":{\"@type\":\"ImageObject\",\"url\":\"https:\\\/\\\/naturdao.com\\\/wp-content\\\/uploads\\\/2024\\\/01\\\/epitelio_DAO_HNMTc-scaled.jpg\",\"width\":2560,\"height\":555},\"datePublished\":\"2024-01-15T12:05:59+01:00\",\"dateModified\":\"2024-03-04T14:07:27+01:00\",\"inLanguage\":\"nl-NL\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/naturdao.com\\\/nl\\\/histamine-en-histamine-intolerantie\\\/#webpage\"},\"isPartOf\":{\"@id\":\"https:\\\/\\\/naturdao.com\\\/nl\\\/histamine-en-histamine-intolerantie\\\/#webpage\"},\"articleSection\":\"Studies, Optioneel\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/nl\\\/histamine-en-histamine-intolerantie\\\/#breadcrumblist\",\"itemListElement\":[{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/nl\\\/#listItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/naturdao.com\\\/nl\\\/\",\"nextItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/nl\\\/category\\\/studies-nl\\\/#listItem\",\"name\":\"Studies\"}},{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/nl\\\/category\\\/studies-nl\\\/#listItem\",\"position\":2,\"name\":\"Studies\",\"item\":\"https:\\\/\\\/naturdao.com\\\/nl\\\/category\\\/studies-nl\\\/\",\"nextItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/nl\\\/histamine-en-histamine-intolerantie\\\/#listItem\",\"name\":\"Histamine en histamine-intolerantie\"},\"previousItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/nl\\\/#listItem\",\"name\":\"Home\"}},{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/nl\\\/histamine-en-histamine-intolerantie\\\/#listItem\",\"position\":3,\"name\":\"Histamine en histamine-intolerantie\",\"previousItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/nl\\\/category\\\/studies-nl\\\/#listItem\",\"name\":\"Studies\"}}]},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/naturdao.com\\\/nl\\\/#organization\",\"name\":\"GLOBAL MOPI SL\",\"description\":\"Complemento alimenticio de Diamino Oxidasa - 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